The main purpose of this thesis is to explore the theoretical and methodological approaches that are involved in understanding how to achieve interaction, communication and collaboration in socio-technical contexts. Hence this thesis seeks for a systemic, ontological framework for understanding and approaching interaction, communication and collaboration processes, which is able to describe the ways we organise in networked societal groups or contexts of interactive participation, within a context of psychological, social, and material relations. Modestos Stavrakis PhD